Colostrum for Skin and Wounds

Skin Health Through Colostrum Nourishment

PRO Colostrum-LD™ is a potent bovine colostrum supplement. It utilizes a unique liposomal delivery system which maximizes the bioavailability of key nutrients that promote optimal skin health from the inside out.

Nutrient-rich PRO Colostrum-LD™ contains immune factors, cytokines, growth factors, lactoferrin, vitamins and minerals. The peptides include epithelial growth factor (EFG), transforming growth factors (TGF-α and TGF-β), fibroblast growth factor (FGF), and insulin-like growth factor (IGF-1). PRO Colostrum-LD™ is certified to contain a minimum of 25-30% immunoglobulins, 1.5% growth hormones, and 3.5% proline-rich polypeptides.

Whether your patients are interested in promoting healthy skin and are seeking a youthful, glowing appearance, or are searching for natural treatments for skin wounds stemming from skin infections, burns, scrapes, cuts or surgical wounds, PRO Colostrum-LD™ is the premier colostrum for skin health supplement that stimulates cellular repair and regrowth.

Colostrum & Wound Healing

Colostrum contains many repair and growth factors that promote healing of tissues including the skin, muscle, cartilage and bone. Numerous animal and human research studies have examined the specific growth factors that are naturally found in colostrum to promote healing of the skin. [1-4]

The healing properties of colostrum have been researched in clinical studies as a topical wound repair treatment for deep wounds. Colostrum applied to the skin has been found to be advantageous over conventional wound dressings because it is easy to apply, protects the wound from infections, increases granulation tissue formation, reduces inflammatory cells, provides pain relief and decreases the number of days required to heal from a deep wound. Patient compliance also increases as less number of dressing changes are required, which can often be quite painful for patients suffering from deep wounds.

PRO Colostrum-LD™ is ideal for use with:

  • Post-surgery wounds
  • Cuts or burns
  • Diabetic ulcers
  • Venous ulcers
  • Trophic ulcers
  • Pressure sores
  • Necrotizing fasciitis
  • Skin infections
  • Inflammatory skin conditions

In a comparative study of colostrum dressing versus conventional dressing for the healing of deep wounds, the researchers Kshirsagar et al., examined the effects of colostrum in patients admitted to a hospital. [1] This study included two hundred patients, between the ages of 20-60, admitted with ulcers and pressure sores (stage II-IV). The patients were randomly assigned to be treated for 15 days in either the colostrum-dressing group (n=100) or conventional-dressing control group (n=100).

The study found that colostrum promoted healing resulting in a decrease in the hospital time required. In the colostrum-dressing group 20% of patients stayed for 3-4 weeks while in the conventional-dressing group 40% stayed for 3-4 weeks.

A significant reduction of ulcer size was demonstrated compared to the control group. In the colostrum-treatment group 18 patients had an ulcer reduction of 91-99%, 50 had a reduction of 81-90%, 20 patients had a reduction of 71-80% and 12 patients had a reduction of 61-70%. This varied significantly from the control group—only 4 patients demonstrated an ulcer reduction size of 91-99%.

A decrease in the number of dressings required was also found in the colostrum for wounds treatment group. In the conventional-treatment group, 45 patients required between 21-25 dressing changes during their hospital stay. This was almost triple of the number of dressing changes required for the colostrum-treatment group. The colostrum-treatment group also reported a significant decrease in pain following colostrum application.

The researchers concluded that several different growth factors in colostrum including nucleotides, epidermal growth factor (EGF), transforming growth factor (TGF), fibroblast growth factors (FGF), and insulin-like growth factor (IGF-I) stimulated cellular growth and repair facilitating in the healing of tissues.

In an animal study, insulin-like growth factor has also been found to increase the process of wound healing in skin lesions induced in diabetic and non-diabetic rats by increasing a higher expression of myofibroblasts in the wound bed and reducing the development of scarring. [2]

An additional study examined the effects of freeze-dried colostrum as an in vitro stimulator of canine fibroblast proliferation and activity. The results of the study concluded that colostrum significantly stimulated dog fibroblasts by promoting cellular repair. [3]

Colostrum & Natural Skin Health and Beauty

Colostrum for Skin and Wounds

PRO Colostrum-LD™ helps restore the natural health and beauty of the skin from the inside out due to its nutrient-rich concentration of immunoglobulins IgG, IgA, IgM, growth factors, lactoferrin and vitamins and minerals.

  • The lactoferrin in colostrum helps to ward off microbes, which is ideal for patients suffering from acne.
  • The immune factors decrease inflammation which can be beneficial for patients with psoriasis and eczema.
  • The growth factors stimulate collagen production and promote skin repair.
  • Epithelial growth factor and fibroblast growth factor aid in the generation and maintenance in the epithelial layer of the skin resulting in the proliferation of new cells and limiting the deterioration of cells associated with the aging process.

Skin conditions are often related to poor gut health and an imbalance in gut and skin microflora. Colostrum promotes skin health by balancing the gut microbiome, eliminating dysbiosis and decreasing intestinal permeability. Research shows that colostrum can restore the gut lining to normal permeability levels and reduce the absorption of toxins and bacteria into the bloodstream. [5,6] Microbial translocation has been implicated in the development of atopic dermatitis. [7]

Bovine colostrum is an effective agent for improving the formation of tight junctions in the epithelial layer of the intestines resulting in reduced intestinal permeability. In a study using rats, the researchers evaluated the damage caused by anti-inflammatory drugs to the gut lining. The non-steroidal anti-inflammatory drug indomethacin, when used alone, caused an increase of intestinal permeability. When indomethacin and colostrum were given together to the animal model treatment group, there was no increase of intestinal permeability. The researchers concluded the bovine colostrum is a novel approach to healing the gut barrier. [6]

A healthy gut promotes healthy skin. Restoring health to the gut with colostrum by improving the microbiome, reducing inflammation and decreasing intestinal permeability can restore overall health to the body resulting in a healthy glowing appearance of the skin. PRO Colostrum-LD™ is natural and safe, and provides multiple health benefits to promote a vibrant, youthful and smooth complexion by providing essential nourishment to the body. Research into the benefits of colostrum for skin are ongoing; many believe the consumption of bovine colostrum for skin conditions like acne, psoriasis and eczema can help to quell the conditions’ symptoms.

Sovereign Laboratories obtains its colostrum from pasture-fed Grade A dairy cows that are certified to be healthy, rBST (synthetic growth hormone), BSE (“mad cow”) and antibiotic-free. Learn more about our industry-leading quality standards here.


  1. Kshirsaga et al. A comparative study of colostrums dressing versus conventional dressing in deep wounds. J Clin Diag Research. 2015 Apr, vol 9(4): PC01-PC04.
  2. Rosi Aparecida Nunes Achar et al. Use of insulin-like growth factor in the healing of open wounds in diabetic and non-diabetic rats. Acta Cirúrgica Brasileira. 2014; Vol. 29 (2): 2014 – 127
  3. Torre , et al. Bovine colostrums increases proliferation of canine skin fibroblasts. J Nutr. 2006;136: 2058S-2060S.
  4. Sporn MB, et al. Polypeptide transforming growth factors isolated from bovine sources and used for wound healing in vivo. Science. 1983.18;219(4590):1329-31.
  5. Prosser C, Stelwagen K, Cummins R, Guerin P, Gill N. Milne C. Reduction in heat induced gastrointestinal hyperpermeability in rats by bovine colostrum and goat milk powders. J App Phys 2004; 96:650-654
  6. Playford RJ, Floyd DN, Macdonald CE, et al. Bovine colostrum is a health food supplement which prevents NSAID induced gut damage. Gut 1999; 44:653-658.
  7. Raone B, Raboni R, Patrizi A. Probiotics reduce gut microbial translocation and improve adult atopic dermatitis. J Clin Gastroenterol. 2014 Jan;48(1):95-6.